Erythropoietin (EPO)

Erythropoietin (EPO) plays a key role in the regulation of red cell mass and erythrocyte production. EPO may be used to aid the differential diagnosis of polycythemia and non-regenerative anaemia. Raised levels of EPO occur in secondary polycythemias and renal tumours. Low/normal levels may occur in renal failure and polycythemia vera.